[Prenatal hypertrophic cardiomyopathy and neonatal noonan syndrome: an association to remember].

We present the case of a girl diagnosed with prenatal hypertrophic cardiomyopathy in week 32 of gestation. In this first pregnancy for an older woman, the fetus had a thickened nuchal fold at the 12-week screening; amniocentesis revealed a normal 46, XX karyotype and polyhydramnios. She was born at 38 weeks of gestation with no complications. She was admitted for study, and physical examination revealed dysmorphic and somewhat coarse features, macrocephaly and macrosomia, wide chest and short limbs, low-set ears, wide nasal bridge, hypertelorism, antimongoloid slanting eyes, carp mouth with a marked philtrum and high arched palate, low rear hairline, and a short, wide neck (Fig. 1); she also had a variable ejection systolic heart murmur in the first few hours of life. The electrocardiogram (Fig. 1) showed biventricular hypertrophy with repolarization changes. A chest X-ray (Fig. 1) showed moderate cardiomegaly, and an echocardio-